1000-1500 word about Candida .albicans pathogenicity (biofilm formation) What is C.albicans? what could C.albicans cause under certain circumstances, statistics of morbidity and mortality- prevalence? Pathogenicity of candida albicans? Important factors influence pathogenicity- focus on morphological transformation, hyphal growth, and biofilm formation, and what genes express those how morphological transformation and biofilm formation contribute to C.albicans pathogenicity- resisting antifungal-host immune system, brifly mention infection stages, adherence, invasion..etc.? Recent studies of pharmacological compounds that inhibit biofilm formation and yeast-to-hyphae transformation, acetylcholine and its role in inhibiting biofilm. Previous studies about pilocarpine and its role in the same field of biofilm inhibition. The signaling pathway through which acetylcholine work, cholinergic anti-inflammatory pathway Types and subtypes of cholinergic receptors targeted by acetylcholine in human Studies show evidence of potential cholinergic receptors possessed by C.albicans, genes express cholinergic receptors (suggested study to be used as reference, beside others, by Borghi201, Toenjes 2005) mention briefly in a paragraph or so about other compounds Clozapine, SIB 1508Ymaleate, PD102807, Cevimeline hydrochloride, and 1-Acetyl-4-methylpiperazine hydrochloride. similar studies employed these compounds, if possible, and type pf receptors targeted by these compounds. Note: 1-coherence and sequencing of the information is required. 2-References should be numbered based on the order of appearance, and first six authors, et. al. In text (citation sequence), i the reference number should be cited in brackets. Vancouver style. 3- SCIENTIFIC ACADEMIC ENGLISH.