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For this week I will discuss the Dengue Virus, I chose this topic because I remember during my school days back in in Brazil we had a discussion on this topic and it gave me a lot of insight because by then I had never heard about that virus.
According to CDC the mode of transmission of the dengue virus is Dengue viruses are spread to people through the bites of infected Aedes species mosquitoes (Ae. aegypti or Ae. albopictus). These are the same types of mosquitoes that spread Zika and Chikungunya.
What type of virus have you chosen (DNA or RNA)?
Ans: Dengue is RNA virus.
Is your virus single stranded or doubled stranded?
Ans: Dengue is a single- stranded virus.
If RNA, is the strand + or -?
Ans: Dengue virus is a single-stranded positive -sensed RNA virus.
What species does the virus infect?
Ans: The Dengue virus mostly infect Humans.
What are the life-cycle stages of the virus?
Ans: After feeding on an DENV-infected person, the virus replicates in the mosquito midgut, before it disseminates to secondary tissues, including the salivary glands. The time it takes from ingesting the virus to actual transmission to a new host is termed the extrinsic incubation period (EIP). The EIP takes about 8-12 days when the ambient temperature is between 25-28C [4-6]. Variations in the extrinsic incubation period are not only influenced by ambient temperature; a number of factors such as the magnitude of daily temperature fluctuations[7, 8], virus genotype [9], and initial viral concentration [10] can also alter the time it takes for a mosquito to transmit virus. Once infectious, the mosquito is capable of transmitting virus for the rest of its life.
What disease does your virus cause?
Ans: Dengue virus causes Hemorrhagic fever.
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