This is the background/introduction part of a larger paper. 5-6 pages of information, Arial 11pt font, single spaced. Any relevant images can be included in the sections, but images are not required. If an image is used please list the source under the image. The section breakdowns should be:
1. general introduction — can be short
2. Ovarian serous cystadenocarcinoma — background info
3. DNA Methylation/Demethylation specific to cancers
4. TET Enzymes overall background and more specific information on TET1 – mechanisms and functions. The difference between TET1 FL and TET1 ALT isoforms.
5. TET1 role in Ovarian Cancer specifically – if any info is available on this
6. The Cancer Genome Atlas background information – what is it? what is used for? etc
7. GDC Data portal information on the OV dataset – OV data set used for analysis so general background information on what is included in this dataset.
8. Any previous relevant information about TET1 in other types of cancers – expression or functional roles
The order of these sections can be moved around and changed depending on the information and flow of the section.
Some relevant info in TET1 Isoforms: https://academic.oup.com/nar/article/45/14/8269/3844757
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