Discuss about various acute Febrile Illnesses (AFI) have emerged, and some are life-threatening. The clinical management of AFI heavily relies on accurate detection of the pathogen, which possibly could be bacteria, virus, fungi or parasites. Upon the outbreak of AFI, it is important for the clinicians to immediately know the causative pathogen so that they could decide and guide proper medications accordingly without delay. Traditional detection systems may take several days to weeks to get a definite conclusion of what the pathogens are. However, genomics or proteomics based assays could tremendously increase the sensitivity, specificity and efficiency of the detection process. Please use Genomic and Proteomic engineering knowledge to propose a strategy to conquer this clinical challenge. You could focus on the detection of the pathogen or the host response.
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